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Article

Predictive model for high-frequency microsatellite instability in colorectal cancer patients over 50 years of age.

Cancer medicine - 1 Jun 2017

Fujiyoshi Kenji, Yamaguchi Tatsuro, Kakuta Miho, Takahashi Akemi, Arai Yoshiko, Yamada Mina, Yamamoto Gou, Ohde Sachiko, Takao Misato, Horiguchi Shin-Ichiro, Natsume Soichiro, Kazama Shinsuke, Nishizawa Yusuke, Nishimura Yoji, Akagi Yoshito, Sakamoto Hirohiko, Akagi Kiwamu

Abstract excerpt

Microsatellite instability (MSI) is an important biomarker for screening for Lynch syndrome, and also of response to immune checkpoint inhibitors. The aim of this study is to create a predictive model to determine which elderly patients with colorectal cancer (CRC) should undergo MSI and/or immunohistochemistry testing on the basis of clinicopathological data. We analyzed a test cohort of CRC patients...

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Identifiers

PMID: 28544821
DOI: 10.1002/cam4.1088
PMCID: PMC5463087

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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