Genetic Variants Associated With Oral Mucositis in Pediatric Patients With Acute Lymphoblastic Leukemia and Lymphoma Undergoing Chemotherapy.

doi:10.1002/1545-5017.70141

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Genetic Variants Associated With Oral Mucositis in Pediatric Patients With Acute Lymphoblastic Leukemia and Lymphoma Undergoing Chemotherapy.

Pediatric blood & cancer - 1 May 2026

Jardim Luisa Comerlato, Botton Mariana Rodrigues, Curra Marina, Gabriel Amanda de Farias, Thieme Stefanie, Zieger Renata de Almeida, Martins Marco Antonio Trevizani, Matte Ursula da Silveira, Brunetto André Tesainer, Gregianin Lauro José, Roesler Rafael, Siebert Marina, Martins Manoela Domingues

Abstract excerpt

BACKGROUND/OBJECTIVES: This study investigated the association between genetic variants and the occurrence of oral mucositis (OM) in pediatric patients with acute lymphoblastic leukemia (ALL) and lymphoma undergoing chemotherapy (CT). METHODS: A retrospective observational longitudinal study was conducted, with daily assessment of OM using the World Health Organization scale and blood samples collected for DNA...

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Identifiers

PMID: 41823204
DOI: 10.1002/1545-5017.70141

Genes

ABCC1
ABCC2
ABCC4
ABCC6
CYP2A7
GSTM1
HSP90AA1
MTHFR

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