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Article

A cross-tissue transcriptome-wide association study reveals GRK4 as a novel susceptibility gene for COPD.

Scientific reports - 18 Nov 2024

Chen Guanglei, Jin Yaxian, Chu Cancan, Zheng Yuhao, Yang Changfu, Chen Yunzhi, Zhu Xing

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disorder with environmental factors being the primary risk determinants. However, genetic factors also substantially contribute to the susceptibility and progression of COPD. Although genome-wide association studies (GWAS) have identified several loci associated with COPD susceptibility, the specific pathogenic genes underlying these loci,...

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Share to Gene Expression Profiling
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39558015
DOI: 10.1038/s41598-024-80122-w
PMCID: PMC11574126

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