Article
Whole-genome association analysis of treatment response in obsessive-compulsive disorder.
Molecular psychiatry - 1 Feb 2016
Qin H, Samuels J F, Wang Y, Zhu Y, Grados M A, Riddle M A, Greenberg B D, Knowles J A, Fyer A J, McCracken J T, Murphy D L, Rasmussen S A, Cullen B A, Piacentini J, Geller D, Stewart S E, Pauls D, Bienvenu O J, Goes F S, Maher B, Pulver A E, Valle D, Lange C, Mattheisen M, McLaughlin N C, Liang K-Y, Nurmi E L, Askland K D, Nestadt G, Shugart Y Y
Abstract excerpt
Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide association study (GWAS). To identify specific g...
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