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Article

Gene Mutations and Related Molecular Events in Distant Metastasis of Cervical Cancer: A Review.

International journal of medical sciences - 1 Jan 2026

Guo Yinghua, Li Shilong, Liu Tingting, Chang Xiaolong, Qin Peiyan, Wang Nan, Jiang Yingxiao, Lv Na, Li Niannian, Hao Furong

Abstract excerpt

Cervical cancer, a serious gynecological malignancy, often leads to poor patient prognosis due to distant metastasis. The metastasis mechanism is not fully understood. This study explores the link between gene mutations and distant metastasis in cervical cancer. PDGFRA, TP53, and PIK3CA mutations significantly influence metastasis. Despite its low incidence, PDGFRA mutation is closely tied to lymph node and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

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Source

Open in PubMed Open full text

Identifiers

PMID: 41799769
DOI: 10.7150/ijms.123727
PMCID: PMC12964585

Genes

PDGFRA
PIK3CA
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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