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Article

[Prognostic stratification value of MLH1 promoter methylation in endometrioid endometrial carcinomas with a dMMR molecular phenotype].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Mar 2026

Leng H, Song Z X, Liu Y, Wang Y X, Yang J, Hu A J, Wang D D, Zhao X Y, Liu L C, Liu C R

Abstract excerpt

Objective: To investigate the prognostic stratification value of MLH1 promoter methylation in a mismatch repair deficiency (dMMR)-type endometrioid endometrial carcinoma (EEC). Methods: A total of 338 patients with confirmed diagnosis of dMMR EEC at Third Hospital of Peking University Health Science Center, from July 2005 to June 2023 were analyzed. Based on the promoter methylation, they were classified into a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41795988
DOI: 10.3760/cma.j.cn112151-20250708-00453

Genes

MET
MLH1
CCL21
CXCL2
FOXA1
NF1
SOX2
CHD4
RET
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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