Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIK3CA Polymorphisms in Cervical Cancer: Differential Impact of rs6443624 and rs141178472.

Asian Pacific journal of cancer prevention : APJCP - 1 Mar 2026

Srivastava Harshi, Raghuvanshi Shivanjali, Bhalla Shalini, Raghuvanshi Snehkiran, Singh Alok, Singh Ajay Kumar, Singh Nisha, Nigam Nitu, Sonkar Gyanendra Kumar, Iqbal Zeeshan, Prakash Shantanu

Abstract excerpt

BACKGROUND: Cervical cancer remains a major cause of mortality in low- and middle-income settings. We assessed whether two PIK3CA single-nucleotide polymorphisms (SNPs) rs6443624 (A/C) and rs141178472 (C/T) are associated with disease risk, clinicopathological features, and survival. MATERIALS AND METHODS: In a prospective case control study at a tertiary center, 154 participants were enrolled (77 cases, 77...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenocarcinoma
Share to Biomarkers, Tumor
Share to Carcinoma, Squamous Cell
Share to Class I Phosphatidylinositol 3-Kinases
Share to Follow-Up Studies
Share to Prognosis
Share to Survival Rate
Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 41793685
DOI: 10.31557/APJCP.2026.27.3.1061

Genes

PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIK3CA Polymorphisms in Cervical Cancer: Differential Impact of rs6443624 and rs141178472.PMID 41793685Read ↗

Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix.Semantic proximity Read ↗

Oncogenic impact of PIK3CA, KRAS, and PTEN mutations in cervical cancer among South Indian women.Semantic proximity Read ↗

Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcomeSemantic proximity Read ↗

Dissection of PIK3CA Aberration for Cervical Adenocarcinoma OutcomesSemantic proximity Read ↗

Mutation of PIK3CA: possible risk factor for cervical carcinogenesis in older women.Semantic proximity Read ↗

Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome.Semantic proximity Read ↗

Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway.Semantic proximity Read ↗

Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study.Semantic proximity Read ↗

PIK3CA mutation and CNV status and post-chemoradiotherapy survival in patients with cervical cancer.Semantic proximity Read ↗

Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis.Semantic proximity Read ↗

Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery.Semantic proximity Read ↗

Association of rs2279744 and rs117039649 promoter polymorphism with the risk of gynecological cancer: A meta-analysis of case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.