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Article

Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study.

The Lancet. Oncology - 1 Apr 2021

Bowden Sarah J, Bodinier Barbara, Kalliala Ilkka, Zuber Verena, Vuckovic Dragana, Doulgeraki Triada, Whitaker Matthew D, Wielscher Matthias, Cartwright Rufus, Tsilidis Konstantinos K, Bennett Phillip, Jarvelin Marjo-Riitta, Flanagan James M, Chadeau-Hyam Marc, Kyrgiou Maria

Abstract excerpt

BACKGROUND: Most uterine cervical high-risk human papillomavirus (HPV) infections are transient, with only a small fraction developing into cervical cancer. Family aggregation studies and heritability estimates suggest a significant inherited genetic component. Candidate gene studies and previous genome-wide association studies (GWASs) report associations between the HLA region and cervical cancer. Adopting a...

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Identifiers

PMID: 33794208
DOI: 10.1016/S1470-2045(21)00028-0
PMCID: PMC8008734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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