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Article

The effect of hyper-induced SOS response on evolution in Escherichia coli.

BMC microbiology - 7 Mar 2026

Zhao Ruoxuan, Jelsbak Lars, Zhao Yufei, Olsen John Elmerdahl, Thomsen Line Elnif

Abstract excerpt

BACKGROUND: The SOS response, a conserved bacterial DNA repair system, plays a critical role in adaptation under stress, by inducing spontaneous mutations. This study compared the evolutionary dynamics of Escherichia coli and a derivative of this strain with a constitutively activated SOS response (SOS*), focusing on growth phenotype, competitive fitness, genome evolution, and metabolism over 90 days of...

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Share to Adaptation, Physiological
Share to Escherichia coli Proteins
Share to Genetic Fitness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Metabolic Networks and Pathways

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Share to SOS Response, Genetics

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Source

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Identifiers

PMID: 41792597
DOI: 10.1186/s12866-026-04877-0
PMCID: PMC13081320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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