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Article

Newborn screening for type 1 diabetes using genome-based risk scores in the Early Check program.

American journal of human genetics - 2 Apr 2026

Gaddis Nathan C, Kucera Katerina S, Cope Heidi L, Carter Javan K, Forsythe Ana N, Gwaltney Angela, Sullivan Jennifer, Crissman Blythe, Fraser Diane P, Page Grier P, Jalazo Elizabeth, Law Jennifer R, Scharfe Curt, Peay Holly L

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease that often presents in childhood and can lead to life-threatening complications such as diabetic ketoacidosis. Genetic risk scores (GRSs) offer an innovative approach to early identification of T1D risk, but their integration into newborn screening (NBS) has not been implemented at scale in the United States. We evaluated the feasibility of using whole-genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41791391
DOI: 10.1016/j.ajhg.2026.02.010
PMCID: PMC13080785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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