Article

Successful incorporation of a genetic risk prediction research platform into routine newborn screening

2021-03-01

Abstract excerpt

<h4>ABSTRACT</h4> An increasing number of diseases can be offered treatments that are transformative if administered in a timely manner. However, many of these diseases are currently not included in the newborn screening programs because they lack sensitive and specific metabolic biomarkers, and detection of children at increased risk relies on genetic methods. Type 1 diabetes (T1D) constitutes a potential example...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f1bc1e39-db99-5271-9f7c-f07583beec38
DOI: 10.1101/2021.02.26.21252305

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Successful incorporation of a genetic risk prediction research platform into routine newborn screeningDOI 10.1101/2021.02.26.21252305Read

Newborn screening for type 1 diabetes using genome-based risk scores in the Early Check program.Semantic proximity Read

Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials—GPPAD‐02 study design and first resultsSemantic proximity Read

Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case-control study.Semantic proximity Read

Found in Translation: A Type 1 Diabetes Genetic Risk Score Applied to Clinical Diagnosis.Semantic proximity Read

Beyond Arrays: Leveraging Whole Genome Sequencing to provide insights into Type 1 Diabetes risk in the populationSemantic proximity Read

Towards needed improvements in inherited metabolic medicine in adulthood: The SIMMESN adult metabolic working group and MetabERN Joint Position Statement.Semantic proximity Read

Genomic newborn screening: feasibility, acceptability and clinical outcomesSemantic proximity Read

The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study.Semantic proximity Read

A type 1 diabetes prediction model has utility across multiple screening settings with recalibrationSemantic proximity Read

Early life phenotypes of type 1 diabetes genetic riskSemantic proximity Read

For parents. Type 1 Diabetes TrialNet. From early detection to possible prevention.Semantic proximity Read

Genetics of circulating proteins in newborn babies at high risk of type 1 diabetesSemantic proximity Read