Article
microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2013
Navarro Alba, Clot Guillem, Prieto Miriam, Royo Cristina, Vegliante Maria Carmela, Amador Virginia, Hartmann Elena, Salaverria Itziar, Beà Sílvia, Martín-Subero Jose Ignacio, Rosenwald Andreas, Ott German, Wiestner Adrian, Wilson Wyndham H, Campo Elías, Hernández Luis
Abstract excerpt
PURPOSE: microRNAs (miRNA) are posttranscriptional gene regulators that may be useful as diagnostic and/or prognostic biomarkers. We aim to study the expression profiles of a high number of miRNAs and their relationship with clinicopathologic and biologic relevant features in leukemic mantle cell lymphomas (MCL). EXPERIMENTAL DESIGN: Expression profiling of 664 miRNAs was investigated using a high-throughput...
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