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Article

A multiplex allele-specific polymerase chain reaction assay for rapid and affordable detection of APOL1 risk variants.

Scientific reports - 3 Mar 2026

Adebayo Oyindamola Christiana, Bongaers Inge, Levtchenko Elena, van den Heuvel Lambertus, Labarque Veerle

Abstract excerpt

Non-communicable diseases, such as chronic kidney disease (CKD), are becoming increasingly prevalent worldwide. Genetic factors, including apolipoprotein L1 (APOL1) risk variants (G1 and G2), have been identified as modifiers for the development and progression of CKD, particularly predisposing individuals of African descent to kidney disease. Identifying these risk variants is therefore crucial for enabling...

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Share to Apolipoprotein L1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotyping Techniques

Share to Multiplex Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

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Source

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Identifiers

PMID: 41775776
DOI: 10.1038/s41598-026-41971-9
PMCID: PMC13066572

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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