Article
Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis.
International forum of allergy & rhinology - 1 Mar 2017
Calton Joshua B, Koripella Pradeep C, Willis Amanda L, Le Christopher H, Chiu Alexander G, Chang Eugene H
Abstract excerpt
BACKGROUND: Cystic fibrosis (CF) heterozygotes with a single mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are at significantly higher risk to develop chronic rhinosinusitis (CRS). However the reasons why remain unknown. We tested the hypothesis that CFTR heterozygotes would have smaller sinus volumes than healthy controls. To exclude sinus disease as a confounding factor we also...
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