Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis.

doi:10.1002/alr.21874

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Article

Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis.

International forum of allergy & rhinology - 1 Mar 2017

Calton Joshua B, Koripella Pradeep C, Willis Amanda L, Le Christopher H, Chiu Alexander G, Chang Eugene H

Abstract excerpt

BACKGROUND: Cystic fibrosis (CF) heterozygotes with a single mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are at significantly higher risk to develop chronic rhinosinusitis (CRS). However the reasons why remain unknown. We tested the hypothesis that CFTR heteroz...

Topics

Adult
Aged
Case-Control Studies
Chronic Disease
Cystic Fibrosis Transmembrane Conductance Regulator
Endoscopy
Female
Genotype
Heterozygote
Humans
Male
Middle Aged
Mutation
Paranasal Sinuses
Rhinitis
Sinusitis

Source

Open in PubMed

Identifiers

PMID: 27860385
DOI: 10.1002/alr.21874

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27860385-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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