Article
Correlations between cystic fibrosis genotype and sinus disease severity in chronic rhinosinusitis.
The Laryngoscope - 1 Aug 2018
Abuzeid Waleed M, Song Changeun, Fastenberg Judd H, Fang Christina H, Ayoub Noel, Jerschow Elina, Mohabir Paul K, Hwang Peter H
Abstract excerpt
OBJECTIVE: Cystic fibrosis (CF) patients commonly develop chronic rhinosinusitis (CRS). The impact of the most common cystic fibrosis transmembrane conductance regulator (CFTR) mutation, F508del, on the severity of sinonasal disease remains inconclusive. The objective of this study is to evaluate the impact of CFTR genotype functional classification on sinonasal disease severity in patients with CRS. METHODS:...
Topics
- Adult
- Chronic Disease
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Mutation
- Paranasal Sinuses