Gastroesophageal reflux disease increases the risk of rheumatoid arthritis: a bidirectional two-sample Mendelian randomization study.

Abstract excerpt

Rheumatoid arthritis (RA) is a common autoimmune disease, and some observational studies have indicated an association between Gastroesophageal Reflux Disease (GERD) and RA. However, the causal relationship between the two remains uncertain. We used Mendelian randomization (MR) to assess the causal relationship between GERD and RA. Two-sample Mendelian randomization analysis was performed using pooled data from...

Topics

Join the communities discussing this publication.

• Arthritis, Rheumatoid
• Gastroesophageal Reflux
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Mendelian Randomization Analysis