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Article

Rheumatoid arthritis and idiopathic pulmonary fibrosis: a bidirectional Mendelian randomisation study.

Thorax - 20 May 2024

Leavy Olivia C, Kawano-Dourado Leticia, Stewart Iain D, Quint Jennifer K, Solomon Joshua J, Borie Raphael, Crestani Bruno, Wain Louise V, Jenkins Gisli, Dieudé Philippe, Minelli Cosetta

Abstract excerpt

BACKGROUND: A usual interstitial pneumonia (UIP) pattern of lung injury is a key feature of idiopathic pulmonary fibrosis (IPF) and is also observed in up to 40% of individuals with rheumatoid arthritis (RA)-associated interstitial lung disease (RA-ILD). The RA-UIP phenotype could result from either a causal relationship of RA on UIP or vice versa, or from a simple co-occurrence of RA and IPF due to shared...

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Share to Arthritis, Rheumatoid
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Idiopathic Pulmonary Fibrosis

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Identifiers

PMID: 38649271
DOI: 10.1136/thorax-2023-220856
PMCID: PMC11137470

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