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Article

Peripheral Expression of Dopamine Genes as a Biomarker for Cocaine Addiction in Humans.

European addiction research - 1 Jan 2026

Kigar Stacey L, Lim Tsen Vei, Turner Lorinda, Bullmore Edward T, Ersche Karen D

Abstract excerpt

<p>Introduction: Objective measures for the severity of addiction are needed to identify and appropriately stratify patients into effective treatment groups for intervention and recovery. Our aim was to determine if blood-derived, dopamine-related biomarkers hold predictive validity in patients with cocaine use disorder (CUD). METHODS: A total of 349 participants (163 patients with moderate-to-severe CUD and 186...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41722074
DOI: 10.1159/000551119
PMCID: PMC13061397

Genes

DRD2
COMT
DRD3
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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