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Article

PTSD risk associated with a functional DRD2 polymorphism in heroin-dependent cases and controls is limited to amphetamine-dependent individuals.

Addiction biology - 1 Jul 2014

Nelson Elliot C, Heath Andrew C, Lynskey Michael T, Agrawal Arpana, Henders Anjali K, Bowdler Lisa M, Todorov Alexandre A, Madden Pamela A F, Moore Elizabeth, Degenhardt Louisa, Martin Nicholas G, Montgomery Grant W

Abstract excerpt

Posttraumatic stress disorder (PTSD), a pathologic response to severe stress, is a common co-morbid disorder in substance-dependent individuals. Evidence from twin studies suggests that PTSD is moderately heritable. Genetic association studies to date have reported a limited number of replicated findings. We conducted a candidate gene association study in trauma-exposed individuals within the Comorbidity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 23647975
DOI: 10.1111/adb.12062
PMCID: PMC3883923

Genes

DRD2
DBH
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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