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Article

Biomarkers and advances in AML-MRC: from bench to bedside.

Annals of hematology - 19 Feb 2026

Meng Fanlin, Al-Khafaji Zahraa, Muzammil Khursheed, Sarbazjoda Ehsan, Khaksari Mohammad Navid, Bayani Alireza, Soleimani Samarkhazan Hamed

Abstract excerpt

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) represents a high-risk subtype of AML, characterized by poor prognosis and limited therapeutic options. Recent updates in the WHO and ICC classifications have redefined AML-MRC, emphasizing molecular and cytogenetic criteria over morphological features alone. This review provides a comprehensive overview of the pathogenesis, key biomarkers, and...

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Share to Neoplasm, Residual
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Biomarkers, Tumor

Share to High-Throughput Nucleotide Sequencing

Share to Leukemia, Myeloid, Acute

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Source

Open in PubMed Open full text

Identifiers

PMID: 41711916
DOI: 10.1007/s00277-026-06805-8
PMCID: PMC12920406

Genes

FLT3
IDH1
RUNX1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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