Article
An overview of novel therapies in advanced clinical testing for acute myeloid leukemia.
Expert review of hematology - 1 Feb 2023
Venugopal Sangeetha, Xie Zhuoer, Zeidan Amer M
Abstract excerpt
INTRODUCTION: The past decade has seen a sea change in the AML landscape with vastly improved cognizance of molecular pathogenesis, clonal evolution, and importance of measurable residual disease. Since 2017, the therapeutic armamentarium of AML has considerably expanded with the approval of midostaurin, enasidenib, ivosidenib, gilteritinib, and venetoclax in combination with hypomethylating agents and others....
Topics
- Humans
- Leukemia, Myeloid, Acute
- Mutation
- Recurrence
- Bridged Bicyclo Compounds, Heterocyclic
