Article
Rapid Eye Movement Sleep Behavior Disorder with Clinical Dementia with Lewy Bodies Phenotype but Lacking Postmortem Central Nervous System Synuclein Pathology: Alternate Etiologies.
Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2026
Mayà Gerard, Iranzo Alex, Sánchez-Valle Raquel, Serradell Mònica, Parchi Piero, Albajar Inés, Aizpurua Miren, Aldecoa Iban, Gelpi Ellen
Abstract excerpt
INTRODUCTION: Idiopathic rapid eye movement (REM) sleep behavior disorder (IRBD) has been linked to the synucleinopathies. METHODS AND RESULTS: An 80-year-old man treated with venlafaxine for depression presented with IRBD. Cerebrospinal fluid (CSF) α-synuclein seeding amplification assay (SAA) was negative. During 16 years of follow up he was diagnosed with dementia with Lewy bodies. He died at the age of...
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