Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uptake of cascade tests in relatives of patients undergoing cancer precision medicine in Japan.

Japanese journal of clinical oncology - 7 May 2026

Matsubayashi Hiroyuki, Kiyozumi Yoshimi, Ishihara Eiko, Harada Rina, Higashigawa Satomi, Fushiki Kunihiro, Nishimura Seiichiro, Kado Nobuhiro, Onozawa Yusuke, Kawata Takuya, Kenmotsu Hirotsugu, Ko Ryo, Serizawa Masakuni

Abstract excerpt

OBJECTIVE: Secondary findings of cancer patients who have undergone cancer precision medicine have been reported; however, cascade test outcomes have not yet been reported in Japan. This study aimed to evaluate the uptake of genetic medicine in cancer patients with germline pathogenic variants (GPVs) and cascade test in their relatives in Japan. METHODS: Referral to genetic counseling, incidence of secondary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Family
Share to Genetic Counseling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Germ-Line Mutation

Share to Neoplasms

Share to Precision Medicine

Share to Young Adult

Source

Identifiers

PMID: 41691475
DOI: 10.1093/jjco/hyag022

Genes

APC
ATM
BAP1
BRCA1
BRCA2
CDK4
CDKN2A
MSH2
RAD51C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uptake of cascade tests in relatives of patients undergoing cancer precision medicine in Japan.PMID 41691475Read ↗

Present status of germline findings in precision medicine for Japanese cancer patients: issues in the current system.Semantic proximity Read ↗

Communication With Clinicians and Relatives About Cascade Genetic Testing in Cancer Patients With Germline Pathogenic Variants.Semantic proximity Read ↗

Cascade genetic testing: an underutilized pathway to equitable cancer care?Semantic proximity Read ↗

Familial Disclosure and Cascade Testing in High-Risk Families is Influenced by Gene Variant Penetrance: Implications for Family based Breast Cancer PreventionSemantic proximity Read ↗

Cancer predisposition analysis and post-disclosure behaviors after screening in Japanese childrenSemantic proximity Read ↗

Cascade testing for hereditary cancer in Singapore: how population genomics help guide clinical policy.Semantic proximity Read ↗

Timely targeted testing for hereditary cancer syndromes - Importance of clinician-facilitated cascade testing in the first year post-diagnosis.Semantic proximity Read ↗

Factors affecting the implementation of cascade testing of patients with BRCA1 or BRCA2 pathogenic germline variants in Japan.Semantic proximity Read ↗

Differences in Cascade Genetic Testing Among Families With Hereditary Cancer Risk.Semantic proximity Read ↗

Cascade Testing for Hereditary Cancer Syndromes: Should We Move Toward Direct Relative Contact? A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Uptake of Cascade Genetic Testing for Hereditary Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Uptake of Cascade Genetic Testing for Hereditary Breast Cancer in the Public Health System in a Middle-Income Country: A Real-World Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.