Cancer predisposition analysis and post-disclosure behaviors after screening in Japanese children

Abstract excerpt

<title>Abstract</title> <p> Germline pathogenic variants in cancer predisposition genes are found in approximately 10% of children with cancer, yet data regarding result disclosure and subsequent clinical actions in Japan remain scarce. To evaluate the frequency of germline pathogenic variants in children and to assess post-disclosure clinical actions, including surveillance and cascade testing in Japan. We retr...

Topics

Open a Topic to create a Post that cites this publication.

• Child
• Genetic Predisposition to Disease
• Genetic Testing
• Germ Cells
• Germ-Line Mutation
• Japan
• Neoplasms
• Precision Medicine

Identifiers and source

Literature Corpus work

90b4fc32-8bfb-51df-9f3d-51b144673e7b

DOI

10.21203/rs.3.rs-8781041/v1