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Familial Disclosure and Cascade Testing in High-Risk Families is Influenced by Gene Variant Penetrance: Implications for Family based Breast Cancer Prevention

2026-05-05

Abstract excerpt

<title>Abstract</title> <p> <bold>Background and Methods:</bold> Point of care genetic testing has grown but cascade testing of At-Risk Relatives (ARR) remains underutilized. Between July and September 2023, we surveyed 912 individuals enrolled in the Cancer Prone Study, a registry of diverse high-risk families who received genetic counseling from cancer genetic experts. We analyzed correlates of familial discl...

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Literature Corpus work: 40f8bae0-9412-59bb-a38c-c6506e1ee0aa
DOI: 10.21203/rs.3.rs-9610726/v1

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