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Article

Calcitonin thresholds for prediction of medullary thyroid carcinoma and its clinical response in MEN2A gene carriers.

The Journal of clinical endocrinology and metabolism - 17 Jun 2026

Prete Alessandro, Matrone Antonio, Romei Cristina, Gambale Carla, Bottici Valeria, Casalini Roberta, Torregrossa Liborio, Molinaro Eleonora, Ugolini Clara, Materazzi Gabriele, Elisei Rossella

Abstract excerpt

PURPOSE: In multiple endocrine neoplasia type 2 (MEN2), clinical management of gene carriers (GCs) is still debated, especially in MEN2A. We aimed to evaluate the predictive value of preoperative CTN for medullary thyroid cancer (MTC) diagnosis and excellent response (ER) in MEN2A GCs. METHODS: Retrospective evaluation from a prospectively maintained database of 106 GCs who underwent surgery and were followed up...

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PMID: 41689466
DOI: 10.1210/clinem/dgag041

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RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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