Article
Fundamentals and recent advances in the evaluation and management of medullary thyroid carcinoma.
Molecular and cellular endocrinology - 1 Oct 2024
Gigliotti Benjamin J, Brooks Jennifer A, Wirth Lori J
Abstract excerpt
Medullary thyroid carcinoma (MTC) is a rare primary neuroendocrine thyroid carcinoma that is distinct from other thyroid or neuroendocrine cancers. Most cases of MTC are sporadic, although MTC exhibits a high degree of heritability as part of the multiple endocrine neoplasia syndromes. REarranged during Transfection (RET) mutations are the primary oncogenic drivers and advances in molecular profiling have...
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