Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities in chronic lymphocytic leukemia patients.

Cancer reports (Hoboken, N.J.) - 1 Mar 2023

Sadria Reza, Motamed Nasrin, Saberi Anvar Mohammad, Mehrabani Yeganeh Hassan, Poopak Behzad

Abstract excerpt

BACKGROUND AND AIM: Chronic lymphocytic leukemia (CLL) is a monoclonal malignancy of B lymphocytes. Since common mutations in NOTCH1 and SF3B1, along with other possible chromosomal alterations, change disease severity and survival of patients with CLL, we aimed to evaluate the correlation of common mutations in NOTCH1 and SF3B1 as the poor prognostic markers with chromosomal abnormalities and clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to Leukemia, Lymphocytic, Chronic, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Phosphoproteins

Share to Prognosis

Share to Receptor, Notch1

Share to RNA Splicing Factors

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 36411516
DOI: 10.1002/cnr2.1757
PMCID: PMC10026310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities in chronic lymphocytic leukemia patients.PMID 36411516Read ↗

NOTCH1 and SF3B1 mutations in chronic lymphocytic leukemia with their clinical associations.Semantic proximity Read ↗

Identification of prognostic parameters in CLL with no abnormalities detected by chromosome banding and FISH analyses.Semantic proximity Read ↗

Genetic Abnormalities in Chronic Lymphocytic Leukemia: Where We Are and Where We GoSemantic proximity Read ↗

IMMUNOPHENOTYPE OF LEUKEMIC CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS WITH NOTCH1 AND SF3B1 GENE MUTATIONS.Semantic proximity Read ↗

SF3B1 and IGHV gene mutation status predict poor prognosis in Japanese CLL patients.Semantic proximity Read ↗

Genomic Features: Impact on Pathogenesis and Treatment of Chronic Lymphocytic Leukemia.Semantic proximity Read ↗

Prognostic factors and risk stratification in chronic lymphocytic leukemia.Semantic proximity Read ↗

Prognostic impact of NOTCH1, MYD88, and SF3B1 mutations in Polish patients with chronic lymphocytic leukemia.Semantic proximity Read ↗

[Molecular Prognostic Markers and Their Clinical Relevance in Chronic Lymphocytic Leukemia].Semantic proximity Read ↗

The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia.Semantic proximity Read ↗

Novel prognostic molecular factors: a quantum leap in the field of chronic lymphocytic leukemia.Semantic proximity Read ↗

Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.