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18 F-DOPA PET Silence in High-grade Glioma Subtype F : A Distinct Metabolic Phenotype.

Clinical nuclear medicine - 1 Aug 2026

Quéré Chloé, Bielle Franck, Picca Alberto, Nichelli Lucia, Mathon Bertrand, Kas Aurélie, Rozenblum Laura

Abstract excerpt

The 2021 WHO classification distinguishes adult-type diffuse gliomas as astrocytoma, oligodendroglioma, and glioblastoma. Recently, a new epigenetic subtype-high-grade glioma IDH-wildtype, subtype F (HGG-F)-has been described, characterized by gliomatosis-like infiltration, low proliferative index, and unexpectedly prolonged survival despite a grade 4 methylation profile. We report the first HGG-F evaluated with...

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PMID: 41686054
DOI: 10.1097/RLU.0000000000006358

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