Article
Multiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas.
Journal of neuro-oncology - 1 Sept 2020
Tatekawa Hiroyuki, Hagiwara Akifumi, Uetani Hiroyuki, Yao Jingwen, Oughourlian Talia C, Bahri Shadfar, Wang Chencai, Raymond Catalina, Lai Albert, Cloughesy Timothy F, Nghiemphu Phioanh L, Liau Linda M, Pope Whitney B, Salamon Noriko, Ellingson Benjamin M
Abstract excerpt
PURPOSE: To assess whether hypermetabolically-defined regions of interest (ROIs) on 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (PET) could be used to evaluate physiological features and whether there are measurable differences between molecular subtypes and tumor grades. METHODS: Sixty-eight treatment-naïve glioma patients who underwent FDOPA PET and magnetic resonance...
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