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Article

Pre-operative dual-time-point [18F]FET PET differentiates CDKN2A/B loss and PIK3CA mutation status in adult-type diffuse glioma: a single-center prospective study.

European journal of nuclear medicine and molecular imaging - 1 Jan 2025

Lee Dong Yun, Oh Jungsu S, Kim Jeong Won, Oh Minyoung, Oh Seung Jun, Lee Seungjoo, Kim Young-Hoon, Kim Jeong Hoon, Nam Soo Jeong, Song Sang Woo, Kim Jae Seung

Abstract excerpt

PURPOSE: While [18F]FET PET plays a complementary role in glioma imaging, it needs to be more comprehensively understood for improved characterization of glioma prior to surgery given the evolving landscape of molecular neuropathology. Thus, we investigated the utility of pre-operative dual-time-point [18F]FET PET in correlation with next-generation sequencing (NGS) data in patients with adult-type diffuse glioma...

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Identifiers

PMID: 39365462
DOI: 10.1007/s00259-024-06935-z

Genes

CDKN2A
PIK3CA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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