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Article

Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2025

Engstrom Allison C, Alitin John Paul M, Kapoor Arunima, Dutt Shubir, Lohman Trevor, Sible Isabel J, Marshall Anisa J, Shenasa Fatemah, Gaubert Aimée, Ferrer Farrah, Nguyen Amy, Bradford David Robert, Rodgers Kathleen, Sordo Lorena, Head Elizabeth, Shao Xingfeng, Wang Danny J J, Nation Daniel A

Abstract excerpt

INTRODUCTION: Older adults with mild cognitive impairment (MCI) exhibit deficits in cerebrovascular reactivity (CVR), suggesting CVR is a biomarker for vascular contributions to MCI. This study examined if spontaneous CVR is associated with MCI and memory impairment. METHODS: One hundred sixty-one older adults free of dementia or major neurological/psychiatric disorders were recruited. Participants underwent...

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Identifiers

PMID: 39555916
DOI: 10.1002/alz.14396
PMCID: PMC11772704

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