Article
Cerebrovascular risk factors in Alzheimer's disease: brain hemodynamics and pharmacogenomic implications.
Neurological research - 1 Sept 2003
Cacabelos Ramón, Fernández-Novoa Lucía, Lombardi Valter, Corzo Lola, Pichel Victor, Kubota Yasuhiko
Abstract excerpt
Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood flow shows a reduced velocity and increased pulsatility (PI) and resistance indices (RI) in...
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