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Male Rats Carrying the Taiep Mutation Show Alterations in the Dendritic Arborization of CA1 and CA3 Neurons.

Hippocampus - 1 Mar 2026

Medina-Flores Fernanda, Bravo-Durán Dolores Adriana, Robles-Soto Ricardo, Silva-Gómez Adriana Berenice

Abstract excerpt

The taiep rat originated from a spontaneous mutation in a colony of Sprague-Dawley rats, whose phenotype is inherited as an autosomal recessive trait. The mutant taiep rat shows hypomyelination and demyelination of the central nervous system (CNS) and has been considered a chronic animal model of multiple sclerosis and tubulinopathies. Unlike taiep rats, heterozygous rats for the mutation (+/-), referred to as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41685412
DOI: 10.1002/hipo.70080

Genes

CA1
CA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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