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Article

Circulating cell-free DNA profiling reveals ancestry-dependent genetic variation in metastatic prostate cancer.

Molecular biomedicine - 12 Feb 2026

Maleknia Samaneh, Hassoun Rebecca, Adra Nabil, Shahbazi Reza

Abstract excerpt

African American men experience markedly higher prostate cancer incidence and mortality yet remain underrepresented in genomic studies aimed at identifying ancestry-associated molecular drivers of disease progression. Circulating cell-free DNA (cfDNA) provides a minimally invasive means of capturing tumor-derived genomic alterations and enables broad characterization of molecular heterogeneity. In this study, we...

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Identifiers

PMID: 41673362
DOI: 10.1186/s43556-026-00405-8
PMCID: PMC12894460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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