Article
Genome-wide identification of cis DNA methylation quantitative trait loci in three Southeast Asian Populations.
Human molecular genetics - 12 May 2021
Kassam Irfahan, Tan Sili, Gan Fei Fei, Saw Woei-Yuh, Tan Linda Wei-Lin, Moong Don Kyin Nwe, Soong Richie, Teo Yik-Ying, Loh Marie
Abstract excerpt
DNA methylation (DNAm) is an epigenetic modification that acts to regulate gene transcription, is essential for cellular processes and plays an important role in complex traits and disease. Variation in DNAm levels is influenced by both genetic and environmental factors. Several studies have examined the extent to which common genetic variation influences DNAm (i.e. mQTLs), however, an improved understanding of...
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