Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Superoxide dismutase impacts extracellular vesicle shedding and uptake.

Free radical biology & medicine - 1 Apr 2026

Prova Nahin Siara, Elsayyid Malek W, Tanis Jessica E

Abstract excerpt

Extracellular vesicles (EVs), which transfer bioactive macromolecules between cells, play a critical role in the pathogenesis of multiple neurodegenerative diseases. Focus has centered on how altered EV contents propagate disease and on the potential for EVs as diagnostic biomarkers, while the effects of pathogenic factors on EV release are poorly understood. Using a functional endogenous reporter, we showed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Extracellular Vesicles

Share to Neuroglia

Share to Sensory Receptor Cells

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Source

Open in PubMed Open full text

Identifiers

PMID: 41672113
DOI: 10.1016/j.freeradbiomed.2026.02.008
PMCID: PMC13202618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Superoxide dismutase impacts extracellular vesicle shedding and uptake.PMID 41672113Read ↗

Superoxide dismutase impacts extracellular vesicle biogenesis and uptakeSemantic proximity Read ↗

Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomersSemantic proximity Read ↗

Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomers.Semantic proximity Read ↗

Glia detect and mount a protective response to loss of dendrite substructure integrity in <i>C. elegans</i>Semantic proximity Read ↗

C. elegans ciliated sensory neurons release extracellular vesicles that function in animal communication.Semantic proximity Read ↗

Phosphatidylinositol 4,5-bisphosphate Impacts Extracellular Vesicle Shedding from <i>C. elegans</i> Ciliated Sensory NeuronsSemantic proximity Read ↗

Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegenerationSemantic proximity Read ↗

Fused in sarcoma regulates glutamate signaling and oxidative stress response.Semantic proximity Read ↗

Polycystin-2 ciliary extracellular vesicle release and targetingSemantic proximity Read ↗

Direct Visualization of Anesthesia-induced Subcellular Dysfunction in Non-Neuronal Tissues of C. elegansSemantic proximity Read ↗

An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans.Semantic proximity Read ↗

Superoxide dismutase SOD-1 modulates C. elegans pathogen avoidance behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.