Article
Animal models of renal fibrosis.
Methods in molecular medicine - 1 Jan 2005
Zeisberg Michael, Soubasakos Mary A, Kalluri Raghu
Abstract excerpt
Most of the present knowledge on pathomechanism of renal fibrosis is based on experimental studies with laboratory animals. Today, a variety of genetic and inducible animal models that mimic primary causes of human disease such as diabetes mellitus, glomerulonephritis, or lupus erythematodes are available. However, only few of these models progress consistently to interstitial fibrosis in the kidney involving...
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