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[Acute myeloid leukemia with mutated RUNX1 at the university hospitals of Strasbourg].

Annales de biologie clinique - 30 Aug 2024

Panaget Baptiste, Mauvieux Laurent, Miguet Laurent, Fornecker Luc-Mathieu, Lioure Bruno, Ledoux Marie-Pierre, Rolland Delphine, Mayeur-Rousse Caroline

Abstract excerpt

RUNX1 is essential during human hematopoiesis. Numerous RUNX1 deregulations have been described, including translocations and germline or somatic mutations. Recurrent de novo RUNX1 mutations in acute myeloid leukemias (AML) prompted the creation of a provisional entity of AML with mutated RUNX1 in the 2016 WHO. In addition, recent genomic studies underlined rare AML patients with plasmacytoid dendritic cell (pDC)...

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PMID: 39210855
DOI: 10.1684/abc.2024.1899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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