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Article

Comprehensive next generation sequencing of middle ear neuroendocrine tumors.

Annals of diagnostic pathology - 1 Jun 2026

Bishop Justin A, Xu Jing, Thompson Lester D R

Abstract excerpt

Middle ear neuroendocrine tumor (MeNET) is a distinctive, uncommon neoplasm of the ear. Previously regarded as "middle ear adenoma" among other names, it was found to be consistently positive for neuroendocrine markers, with differentiation analogous to normal intestinal L cells, and has therefore been classified similarly to other neuroendocrine tumors throughout the body. Nevertheless, MeNETs have an unusual...

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Source

Identifiers

PMID: 41650632
DOI: 10.1016/j.anndiagpath.2026.152620

Genes

ATRX
DNMT3A
EP400
HRAS
NF1
R3HDM2
RB1
SF3B1
STAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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