Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma metabolomics and scar pathogenesis: Insights from Mendelian randomization analysis.

Burns : journal of the International Society for Burn Injuries - 1 Apr 2026

Gong Song, Liang Chen, Wu Haibin, Xu Kai, Yang Ting

Abstract excerpt

BACKGROUND: Scar formation following significant tissue injury remains a major clinical challenge, with metabolic processes and inflammation critically influencing tissue remodeling and fibrotic outcomes. OBJECTIVE: This study aims to elucidate the causal relationships between plasma metabolites and scar pathogenesis using Mendelian randomization (MR). METHODS: By employing a two-sample MR approach, we analyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Burns
Share to Cicatrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Glycopeptides

Share to Mendelian Randomization Analysis

Share to Metabolomics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 41632996
DOI: 10.1016/j.burns.2026.107878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma metabolomics and scar pathogenesis: Insights from Mendelian randomization analysis.PMID 41632996Read ↗

The role of circulating metabolites and gut microbiome in hypertrophic scar: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Metabolomic insights into pulmonary fibrosis: a mendelian randomization study.Semantic proximity Read ↗

Causal Association Between Inflammatory Factors and Hypertrophic Scar: A Two‐Sample Mendelian Randomization StudySemantic proximity Read ↗

The effect of inflammatory cytokines on the risk of hypertrophic scar: a mendelian randomization study.Semantic proximity Read ↗

Unraveling the Causal Relationship Between Blood Metabolites and Acne: A Metabolomic Mendelian Randomization Study.Semantic proximity Read ↗

Reevaluating the Role of ACE Inhibitors in Skin Fibrosis Risk: Evidence from Mendelian RandomizationSemantic proximity Read ↗

Gut microbiota constituents may affect hypertrophic scarring risk through interaction with specific immune cells in a two-step, two-sample Mendelian randomization studySemantic proximity Read ↗

The effect of inflammatory cytokines on the risk of hypertrophic scar: A Mendelian Randomization StudySemantic proximity Read ↗

The relationship between metabolite mediated immune regulatory imbalance and the occurrence of malignant tumors of bone and articular cartilage: a Mendelian randomization study.Semantic proximity Read ↗

Evidence of a causal relationship between blood pressure and pathological scars: a bidirectional Mendelian randomization studySemantic proximity Read ↗

Skin eQTL-Cerebrospinal Fluid Metabolites-Keloid Axis: An Integrative Multi-Omics Mediation Mendelian Randomization Study.Semantic proximity Read ↗

Metabolome-Wide Mendelian Randomization to Evaluate the Causal Association Between Blood Metabolites and RosaceaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.