Article
Unraveling the Causal Relationship Between Blood Metabolites and Acne: A Metabolomic Mendelian Randomization Study.
Journal of cosmetic dermatology - 1 Jan 2025
Li Min, Zhan Dan Dan, Fan Li Li, Wang Yu, Hu Xiao Han, Zhang Ming, Zhou Zhou
Abstract excerpt
BACKGROUND: Acne is a common skin disorder that may be linked to metabolic dysfunction. However, the causal impact of blood metabolites on acne has not been thoroughly investigated. METHODS: We performed a metabolome-wide Mendelian randomization (MR) analysis on 486 blood metabolites and acne using a genome-wide association dataset. The study included preliminary inverse-variance weighted (IVW) analysis,...
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