Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using TraDIS as a complementary approach to long term evolution for mapping adaptive mutations in Escherichia coli.

PLoS genetics - 1 Feb 2026

Milner Mathew T, Sen Hrishiraj, Banzhaf Manuel, Lund Peter A

Abstract excerpt

Long term laboratory-based evolution experiments are a powerful tool that are increasingly being used to study fundamental aspects of evolution and to identify genes that contribute to overall fitness under different conditions. However, even with automation, the time that they take to execute limits the extent to which evolution experiments can be used as part of a high throughput approach to understand the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Directed Molecular Evolution
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Evolution, Molecular

Share to Genetic Fitness

Share to Loss of Function Mutation

Share to Mutation

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 41628264
DOI: 10.1371/journal.pgen.1011860
PMCID: PMC12956098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using TraDIS as a complementary approach to long term evolution for mapping adaptive mutations in Escherichia coli.PMID 41628264Read ↗

Adaptation of Escherichia coli to long-term batch culture in various rich media.Semantic proximity Read ↗

Revisiting the Design of the Long-Term Evolution Experiment with Escherichia coli.Semantic proximity Read ↗

Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium.Semantic proximity Read ↗

Identification and dynamics of a beneficial mutation in a long-term evolution experiment with Escherichia coli.Semantic proximity Read ↗

Quantifying the local adaptive landscape of a nascent bacterial community.Semantic proximity Read ↗

The landscape of transcriptional and translational changes over 22 years of bacterial adaptation.Semantic proximity Read ↗

Long-term phenotypic evolution of bacteria.Semantic proximity Read ↗

Changing fitness effects of mutations through long-term bacterial evolution.Semantic proximity Read ↗

A simple method for genome-wide screening for advantageous insertions of mobile DNAs in Escherichia coli.Semantic proximity Read ↗

Linking genotypic and phenotypic changes in the E. coli long-term evolution experiment using metabolomics.Semantic proximity Read ↗

Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations.Semantic proximity Read ↗

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.