Article
Identification and dynamics of a beneficial mutation in a long-term evolution experiment with Escherichia coli.
BMC evolutionary biology - 29 Dec 2009
Stanek Mark T, Cooper Tim F, Lenski Richard E
Abstract excerpt
BACKGROUND: Twelve populations of E. coli were serially propagated for 20,000 generations in a glucose-supplemented minimal medium in order to study the dynamics of evolution. We sought to find and characterize one of the beneficial mutations responsible for the adaptation and other phenotypic changes, including increased cell size, in one of these populations. RESULTS: We used transposon-tagging followed by...
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