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Article

Deciphering the Role of Sirtuin-1 Gene Polymorphism in Diabetic Nephropathy: A Systematic Review and Meta-Analysis.

Journal of diabetes research - 1 Jan 2026

Moin Hira, Asad Munazza, Waseem Maaz, Zafar Sarim, Syed Hania, Syed Ramsha, Hussain Momina

Abstract excerpt

Sirtuin-1-gene (SIRT1) plays a key role in regulating metabolic and inflammatory processes. This review is aimed at evaluating the association between SIRT1-polymorphisms and diabetic nephropathy susceptibility. Observational-cohort and case-control studies were included. Data extraction followed PRISMA 2020 guidelines, and study quality was assessed using the Newcastle-Ottawa Scale. Meta-analysis was done using...

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Share to Diabetic Nephropathies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 41624996
DOI: 10.1155/jdr/5528647
PMCID: PMC12853138

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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