Article
Cardiovascular-kidney-metabolic syndrome: candidate subtypes and genetic risk factors.
BMC medical genomics - 31 Jan 2026
Donker Hylke C, Bisht Vartika, Dwivedi Om Prakash, Mueller Stefanie, Neijzen Dorien, Ding Zhihao, Lunter Gerton
Abstract excerpt
BACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is increasingly recognized as a distinct disorder with important implications for health outcomes, but its heterogeneity of presentation and genetic underpinning remains poorly understood. We aimed to identify potential CKM subtypes and their genetic basis by analyzing biomarkers and health outcomes in a large biobank. METHODS: Blood and urine biomarkers...
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