Article
Multimodal phenotyping of ARDS: design and preliminary insights from the prospective BIOWARE cohort for precision critical management.
Respiratory research - 13 Feb 2026
Tan Ziqi, Liu Weida, Zhang Song, Yang Mei, Yue Chaofu, Huang Xian, Zhao Keyi, Niu Zuxi, Wang Yongjie, Yu Xin, Yu Xiangyou, Yang Chunbo, Ma Siqing, Sun Qiang, Zhu Zhiqiang, Yang Min, Wang Fang, Zhang Shulin, Su Longxiang, Yang Yingying, Wang Qianlin, Long Yun
Abstract excerpt
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a highly heterogeneous syndrome with substantial mortality, for which existing subphenotyping strategies based on single-modal data have limited ability to guide targeted therapies. A comprehensive, multimodal framework is urgently needed to decipher its complexity and advance precision care. METHODS: The BIOWARE study is a prospective, multicenter cohort...
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