Article
Clinical and Microbiological Characteristics of macrolide-resistant Bordetella pertussis Infection: A case series in Osaka, Japan (2024-2025).
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Feb 2026
Taniguchi Kimihiro, Yamaguchi Takahiro, Isoda Kenichi, Shiomi Masashi, Kawasaki Yasuhiro, Amo Kiyoko, Wakabayashi Yuki, Kawahara Ryuji, Nozaki Masatoshi
Abstract excerpt
BACKGROUND: Although macrolide antibiotics are an effective first-line treatment for pertussis, the global emergence and spread of macrolide-resistant Bordetella pertussis (MRBP) presents a significant threat to antimicrobial treatment strategies. However, the current status of MRBP in Japan remains unclear due to the lack of a surveillance system. This study aimed to highlight the emergence and clinical impact...
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