Article
Whole-genome comparison of two same-genotype macrolide-resistant Bordetella pertussis isolates collected in Japan.
PloS one - 1 Jan 2024
Koide Kentaro, Uchitani Yumi, Yamaguchi Takahiro, Otsuka Nao, Goto Masataka, Kenri Tsuyoshi, Kamachi Kazunari
Abstract excerpt
The emergence of macrolide-resistant Bordetella pertussis (MRBP) is a significant problem because it reduces treatment options for pertussis and exacerbates the severity and spread of the disease. MRBP has been widely prevalent in mainland China since the 2010s and has been sporadically detected in other Asian countries. In Japan, two MRBP clinical strains were first isolated in Tokyo and Osaka between June and...
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