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Sharp rise in high-virulence Bordetella pertussis with macrolides resistance in Northern China

5 Mar 2025

Abstract excerpt

Objective: To elucidate the evolution of antigen genotype and antimicrobial resistance distribution of Bordetella pertussis (B. pertussis) from 2019 to 2023 in northern China.Methods: Polymerase chain reaction (PCR) amplification and sequencing were utilized to identify the seven antigen genotypes (ptxA, ptxC, ptxP, prn, fim2, fim3, tcfA). E-test and Kirby-Bauer (K-B) disc diffusion were employed to determine the...

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PMID: 40042368
DOI: 10.1080/22221751.2025.2475841

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